Novel Biological Activities of Allosamidins
نویسندگان
چکیده
منابع مشابه
Novel biological activities of allosamidins.
Allosamidins, which are secondary metabolites of the Streptomyces species, have chitin-mimic pseudotrisaccharide structures. They bind to catalytic centers of all family 18 chitinases and inhibit their enzymatic activity. Allosamidins have been used as chitinase inhibitors to investigate the physiological roles of chitinases in a variety of organisms. Two prominent biological activities of allo...
متن کاملSynthesis of some Novel Chromenopyrimidine Derivatives and Evaluation of Their Biological Activities
AbstractPyrimidine nucleosides are constituents of fundamental structure of the cells. There has been considerable attentions in the chemistry of pyrimidine derivatives due to having a wide range of biological activities such as antiviral, anti-malarial agents, cytostatic, antithelemintic, antibacterial, adenosine receptor ligands, anti-cancer agents, compounds targeting delayed-type hypersensi...
متن کاملSynthesis of some Novel Chromenopyrimidine Derivatives and Evaluation of Their Biological Activities
AbstractPyrimidine nucleosides are constituents of fundamental structure of the cells. There has been considerable attentions in the chemistry of pyrimidine derivatives due to having a wide range of biological activities such as antiviral, anti-malarial agents, cytostatic, antithelemintic, antibacterial, adenosine receptor ligands, anti-cancer agents, compounds targeting delayed-type hypersensi...
متن کاملBiological activities of novel gyrase inhibitors of the aminocoumarin class.
Thirty-one aminocoumarin antibiotics derived from mutasynthesis experiments were investigated for their biological activities. Their inhibitory activities toward Escherichia coli DNA gyrase were determined in two different in vitro assays: an ATPase assay and a DNA supercoiling assay. The assays gave a similar rank order of the activities of the compounds tested, although the absolute 50% inhib...
متن کاملSynthesis, characterization and biological activities of some novel isatin derivatives
A series of novel (arylimino-2-oxo-2,3-dihydro-indol-1-yl)-acetic acid N'-(4-aryl-2-yl)-hydrazide derivatives (5a-g) were synthesized. The structures of the newly synthesized compounds were characterized by elemental analysis, FT-IR, H-, C-NMR and mass spectroscopy. The compounds were screened in vitro for antibacterial and antifungal activities against some human pathogenic microorganisms by t...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Molecules
سال: 2013
ISSN: 1420-3049
DOI: 10.3390/molecules18066952